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Behav Brain Res 2007
This is the first pharmacological agent to show prognostic benefit in this population, offering therapeutic potential beyond symptomatic control
It is also stable in human gastric juice and has been studied extensively in preclinical models with a strong safety profile across all published literature
Enteroviral 2B protein has been shown to interact with mitochondrial voltage-dependent anion channel 3 (VDAC3) to induce ROS production, and knockdown of VDAC3 significantly reduces EV71-induced mtROS generation and viral replication 132
The first event consists of FAD reduction and the formation of a charge transfer absorption with a maximum at 640 nm
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