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Tirzepatide is a dual GLP-1 and GIP receptor agonist delivered through a once-weekly injection
However, due to its invasiveness, it should be offered preferentially to patients with exhausted non-pharmacological and pharmacological treatment options
It doesn't target weight
This effect was fully suppressed by the microglial inhibitor minocycline and the p38 mitogen-activated protein kinase (MAPK) inhibitor SB203580, underscoring the essential role of microglial activation and the p38 MAPK pathway [72]
Since there is no one-size-fits-all dose, collaborating with an experienced provider is crucial for tailoring the right dosage
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