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Several peptides have been used concurrently with hormone replacement therapy under provider supervision
if a duct is blocked (by a gallstone, scar-like narrowing/stricture, or a tumor), the drug cant reach its target and adding more bile acids can worsen the backup (jaundice, itching, rising bilirubin/ALP)
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Nagar S, Walther S, Blanchard RL: Sulphotranferase (SULT) 1A1 polymorphic variants *1, *2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation
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