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The process of gallstone formation and growth has been shown to be enhanced in the presence of oxidized bilirubin, which is found in gallstones (Sanikidze 2016

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Elis S, Wu Y, Courtland HW, Cannata D, Sun H, Beth-On M, Liu C, Jasper H, Domen H, Karabatas L, Guida C, Basta-Pljakic J, Cardoso L, Rosen CJ, Frystyk J, Yakar S

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For more exploration of the angiogenesis issue, see the article that we have published on potential complications of TB-500