When cellular stress surpasses a reversible threshold, mitochondria-nucleus interactions push cells toward irreversible fates: m decreases, accompanied by ROS overproduction and ATP depletion, while BAX/BAK-mediated MOMP triggers apoptosis [265]
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Ziegler, D., Reljanovic, M., Mehnert, H., and Gries, F
Rectal delivered nanocomposite suppository against radiation-induced proctitis