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This combination is particularly interesting for aging-related tissue deterioration, where both mitochondrial dysfunction and impaired repair signaling contribute to declining tissue health

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To assess the importance of lipidation modification to Cagri, pharmacological comparison of Cagri and its non-lipidated backbone (CagriBB) was undertaken using a cAMP response element (CRE)-reporter assay

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High salt concentrations interfere with copper chelation and can destabilize the peptide complex