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Warning Signs of Dehydration Break your fast immediately if you experience: Dark yellow or amber urine No urination for 8+ hours Dizziness or light-headedness when standing Severe headache Dry mouth and lips that don't improve Extreme fatigue beyond normal Ramadan tiredness Confusion or difficulty concentrating Critical reminder: Drink even if you don't feel thirsty

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Supplementary material The Supplementary Material for this article can be found online at: References 1 Alvarez-SabnJ.DelgadoP.AbilleiraS.MolinaC

Published protocols also note pregnancy, known hypersensitivity to IGF-1 analogs, and pre-existing insulin resistance or diabetes as conditions requiring exclusion or enhanced monitoring in study design

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