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A GH pulse from the pituitary travels to the liver and peripheral tissues, where it drives the production of IGF-1 (insulin-like growth factor 1), the mediator responsible for most of GHs anabolic and recovery-related effects
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Fueling the obesity epidemic
The impaired GLP-1 response observed in obesity and type 2 diabetes has, therefore, been implicated in the pathogenesis of hyperglucagonaemia [63]
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