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The researchers conjecture that the difference between the findings for broader health improvements in GLP-1 clinical trials and in the rollout of these drugs in the general population may result from greater adherence to the GLP-1 regimen for those in clinical trials and from differences in the treatment populations

Sun J, Kumar Panda P, Kumar Samal S, Ahuja R, Ajeganova S, Hafstrm I, Liu A, Frostegrd J (2021) Effects of atorvastatin on Tcell activation and apoptosis in systemic Lupus Erythematosus and novel simulated interactions with Creactive protein and interleukin 6

Diarrhea rates in semaglutide trials typically range from 8% to 15% across dose levels, significantly lower than the 9% to 35% seen with retatrutide

Semaglutide shows a ratio of 1.34

doi: 10.1016/j.mce.2020.111003 161 ChengYLiWGuiRWangCSongJWangZet al