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The purification of GST fusions from mammalian cells using GSH-coupled magnetic beads usually requires the removal of the competitively binding endogenous GSH (Tessema et al., 2006)

Lower concentrations would push injection volumes uncomfortably high

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Although radioprotective substances have been shown to be effective at decreasing the side effects of radiation therapy, there are currently no radioprotectants used in diagnostic radiology

GSH-activated prodrugs, including disulfide- and diselenide-linked conjugates, are selectively activated in tumors, enabling high drug loading and targeted delivery