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Many users of novel weight loss drugs are relieved to be unencumbered of the incessant food noise that once undermined their restraint and prompted relapses after successful weight loss
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The trial tested multiple dose levels over 48 weeks, and the headline result, up to 24.2% body weight reduction at the highest dose, grabbed international attention
The Lancet, 402 (10403), 705-719
The specific neuronal populations that express Glp1r and mediate anti-inflammatory effects, including brainstem populations implicated in peripheral immune sensing, have not been identified
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