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OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases
In the 50s, when chemotherapy wasnt yet available, massive doses of B12 shots were given to children with a neuroblastoma tumor every two days, for 2-3 years with great success: NEUROBLASTOMA: AN EVALUATION OF ITS NATURAL HISTORY AND EFFECTS OF THERAPY, WITH PARTICULAR REFERENCE TO TREATMENT BY MASSIVE DOSES OF VITAMIN B12
MitoQ improved flow-mediated dilation (FMD) by 3.1% in DM2 patients independent of glycemic changes ( Dose-finding phases are critical, given the U-shaped efficacy curve of antioxidants
correct dosing and the 812 week timeline
Chemical demethylation of methylmercury by selenoamino acids
