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PMID 11435445
Treweeke A, Winterburn T, Mackenzie I, et al
CD8 + T lymphocytes can upregulate perforin expression and increase MMP activity, resulting in the airway and lung tissue destruction, as well as chemotactic activation of inflammatory cells through secretion of cytokines such as interferon, IL-12, TNF- and chemokines, exacerbating the inflammatory response
10.1016/j.trim.2022.101701 Transpl
These results provided us with the essential methodology to design the GLP-1 infusion study and provided information on the estimated number of participants needed for adequate statistical power
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