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We are going to uncap our needle and, if youre doing this on yourself, youre going to kind of pinch up a little bit of skin in between your fingers

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Clinicians can respond with risk stratification rather than blanket permission or refusal, especially when GI history or gallbladder risk is relevant

The standard titration approach The clinical trials used specific escalation protocols designed to minimize GI disturbance while still reaching therapeutic dose levels

These tests its safety and efficacy in a larger population prior to approval