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In DSS-induced colitis, the expression of HSP is delineated to decrease, indicating the undermined stress protective mechanism in IECs

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In a 2-year trial, acute pancreatitis was reported in 8 semaglutide-treated patients (0.27 cases per 100 patient-years) and 10 placebo-treated patients (0.33 cases per 100 patient-years), both on a background of standard of care.1 In trials of patients receiving oral semaglutide, pancreatitis was reported as a serious adverse event in 6 patients (0.1 events per 100 patient-years) receiving semaglutide versus 1 in comparator-treated patients (less than 0.1 events per 100 patient-years)

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Studies reveal a strong correlation between the composition of gut microbiome and patient survival

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P values were adjusted for multiple testing using BH FDR correction

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