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Some research findings show that high-protein intake can cause oxidative stress, which may lead to increased risk of chronic disease, including cancer, while other findings did not show any correlation between high-protein diets and long-term increase in ROS levels (271, 274, 275)

281 As approved by the FDA in 2018 for the treatment of ATTR-PN, Inotersen requires regular safety monitoring for potential adverse events, particularly thrombocytopenia and glomerulonephritis

The data suggests it may occur, but with how rare these issues are, I would say the benefits generally should outweigh vision risks

Overall, current data support a favorable benefitrisk profile despite persistent precautionary carcinogenicity warnings

Zinc and copper share common transport pathways, and increasing copper levels without adequate zinc can create functional deficiencies that impair immunity, wound healing, and hormone balance