PloS One (2011) 6(8):e23205
The available human data suggest that GLP-1 receptor agonists are safe and generally well tolerated in both acute and chronic settings, which supports continued investigation
Longstanding or chronic symptoms like mood swings or muscle pain may persist, needing individualised care
Kurusu R, Fujimoto Y, Morishita H, Noshiro D, Takada S, Yamano K, et al
For instance, while many of the GLP-1 drug interactions investigated to date may be statistically significant , no dose adjustment is required because they were not found to be clinically relevant . The one exception is tirzepatide, as described above