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In the SURPASS-1 trial, tirzepatides efficacy and safety in T2DM were shown, with improvements in blood glucose control
The tirzepatide cohort achieved 66% adherence, compared to 48% for semaglutide
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Discussion In this prespecified analysis of the 529 patients randomized in the STEP-HFpEF trial, semaglutide consistently improved HF-related symptoms and physical limitations as measured by KCCQ-CSS, as well as exercise function measured by 6MWD, and reduced body weight and inflammation across the range of LVEF, including in participants with LVEF 60%
Hoppe, C
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