Zhang L, Zhang L, Li L, Hlscher C
Tirzepatide is a dual agonist, working on both GLP-1 and GIP receptors, which produces larger average weight loss in head-to-head trials
Semaglutide works by mimicking the GLP-1 hormone, which helps regulate appetite and slows gastric emptying, promoting feelings of fullness for longer periods
Secondary objectives were change from baseline to week 3 for tirzepatide versus placebo in fasting and postprandial appetite VAS ratings, FCI, FCQ-S, Eating Inventory, PFS questionnaire ratings and BOLD activation to photos of Food HiPal (Food HiF/HiS and Food HiF/HiC ) relative to non-food during the fasting state in the prespecified principal reward ROIs
The cost of GLP-1 medication is not included in the WW Clinic membership fee and depends on the chosen drug and insurance coverage