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Other Safety Considerations A comprehensive review of post-marketing safety data identified that both drugs have been associated with gastrointestinal issues (nausea, vomiting, pancreatitis, diarrhea) as well as potential effects on bone remodeling, kidney function, and thyroid health

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Optimal Timing Protocols Administering doses at appropriate times relative to meals and sleep cycles minimizes gastrointestinal and fatigue-related side effects