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The arrays were scanned using an Agilent G2505C scanner and the fluorescence intensity was analyzed with Agilent Feature Extraction software (version 11.0.1.1)

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Regarding mitochondrial dysfunction involved in AD pathophysiology, it includes disturbances in oxidative phosphorylation (OXPHOS), and impaired energy metabolism as well as excess generation of ROS, altered mitochondrial biogenesis, transport and dynamics (68)