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Key secondary endpoints included non-inferiority of tirzepatide (5 mg) compared to insulin degludec in HbA1c reduction, superiority of all tirzepatide doses over insulin degludec in HbA1c reduction and weight loss, and the proportion of participants achieving an HbA1c level below 7.0% at week 52
Athauda and colleagues 26 reported that exenatide 2 mg once weekly had numerically greater improvements in individual domains assessing mood/depression across all observer rated outcome measures including the mood/apathy domain of the Non-Motor Symptoms Scale in Parkinson Disease
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