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The PKA and EPAC2 pathways are triggered by both receptors'activation of adenylate cyclase, which raises intracellular cAMP and causes insulin synthesis and release, cellular proliferation, and antiapoptotic effects

Nausea was the most common at 46.6%, and vomiting was reported in 30.9% of pill users, which is higher than rates seen with the Wegovy injection

Most headaches resolve within 2-4 weeks as your body adapts to the medication's effects