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In recent years, with the increased understanding of p53's biological function, therapies targeting p53, including small-molecule drugs, cancer immunotherapies targeting p53, and gene therapies targeting p53, have gradually improved
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"We're going to see a kind of tectonic shift in the way people spend money," Freeman, 55, told Business Insider
As the ER lacks glutathione reductase activity, GSSG must be exported to the cytosol by SLC33A1 to maintain redox homeostasis