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The drugs work, at least in part, by activating one or multiple receptors throughout the body, including glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) receptors on cells in the brain, pancreas and elsewhere

Hepatic mRNA abundance (relative to Actb ) for genes associated with ( E ) hepatic gluconeogenesis ( Gck , G6p , Pck , Gsk3 , and Pygl ) and ( F ) insulin signaling ( Gcgr , Igf1 , and Igf1r ) in Dpp4 +/+ ( n = 11) and Dpp4 / ( n = 7) mice

You may experience slight bruising, redness, and soreness at the injection site