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The preclinical safety information for Wegovy adds: In developmental toxicity studies in rabbits and cynomolgus monkeys, increased pregnancy loss and slightly increased incidence of foetal abnormalities were observed at clinically relevant exposures. While the company is now carrying out trials to explore whether such drugs are safe for pregnant women, at present it advises that semaglutide should not be used during pregnancy as it is not known if it may affect an unborn child

Feb 20 Sean Overin GLP-1s, Osteoarthritis, and the Ecosystem of Cartilage Empty space, drag to resize Ive been paying closer attention to the research around GLP-1 medications over the past year

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