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Oxidative biomarkers (total antioxidant status [TAS], total oxidant status [TOS], oxidative stress index [OSI]) and histopathological parameters (muscle atrophy, degeneration, leukocyte infiltration, internalization of nuclei, fragmentation, and hyalinization) were analyzed
PMID: 22381456 | DOI: 10.1016/S0140-6736(11)61452-9 [19] Fakih MG, Pendyala L, Brady W, et al
While the level of evidence for each compound varies, all of them lack the kind of large, well-controlled trials in humans that are necessary to establish safety and effectiveness, which is required for drug approvals
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Should I apply hydroquinone or tretinoin first
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