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For resistance development by sequential passaging, overnight cultures of H

Claim amendments made during prosecution define the scope of the claims through prosecution history estoppel, and those amendments are not visible in the patent itself or in the Orange Book

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Wegovy is approved for use in people with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related medical condition

J Cardiovasc.Pharmacol 2007;50(2):168-175