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Reviews published in 2025 describe a body of research dominated by animal and cell studies, with signals suggesting effects on angiogenesis (the growth of blood vessels), growth-factor signalling (mainly growth hormone) and musculoskeletal healing

doi: 10.3390/microorganisms5010006 76 LiuX.ShaoJ.LiaoY.WangL.JiaY.DongP.et al

The practical takeaway: it is not just how much Ipamorelin is administered but when and specifically how far from food and insulin that shapes the size of the GH pulse in the research framing