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Appreciation of these issues will determine whether the results of an experiment are relevant for understanding mechanisms of cell death and identification of novel therapeutic targets for most patients or if they are clinically irrelevant and just adding background noise to the literature
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The genes ( tphR , tphC , tphA2 , tphA3 , tphB , and tphA1 ) are anticipated to encode for the IclR-type transcriptional regulator, the TPA binding receptor, the large subunit of the oxygenase component of TPA 1,2-dioxygenase (TPADO), the small subunit of the oxygenase component of TPADO, a 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase (DCDDH), and a reductase component of TPADO, respectively
(21(4)):226-229 doi:10.6065/apem.2016.21.4.226
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