In cultured human keratinocytes exposed to UVB radiation (a standard oxidative stress model), pre-treatment with 10 nM GHK-Cu resulted in: 2.8-fold increase in glutathione reductase mRNA (the enzyme regenerating reduced glutathione from its oxidized form) 2.3-fold increase in catalase expression (HO decomposition) 1.9-fold increase in ferritin heavy chain (sequestering iron, another Fenton-active metal) 62% reduction in 8-hydroxy-2-deoxyguanosine (8-OHdG) levels, a DNA oxidative damage marker The protective effect disappeared when using copper-free GHK or copper chloride alone, confirming the intact peptide-copper complex is required
In this guide, well break down how 5-Amino-1MQ works , the science behind its mechanism of action, how it can be stacked with other compounds for greater results, optimal cycling strategies, and important legal considerations before use
Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International Journal of Molecular Sciences, 19(7), 1987
Product Details: Contents: 30g (1 oz) GHK-Cu + BPC-157 Peptide Topical Cream
Dosing & Reconstitution Guide Educational guide for reconstitution and common dosing patterns Standard / Conservative Approach (3 mL = 16.67 mg/mL