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It is much more effective to deliver the intact molecule directly to your system

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overexpressed miR-340-5p in the myocardium by direct myocardial injection of AVV-9 containing miR-340-5p precursor, which targeted inhibition of MyD88 and thus restored declining GSH levels, alleviated insult of cardiac function and oxidative injury induced by sepsis in the hearts of mice [253]

Instead, its added as a booster, or push, toward the end of an IV session