Testosterone plays a central role in regulating muscle mass, fat storage, and insulin sensitivity, and declining levels are associated with increased fat mass particularly visceral, or abdominal, fat, and a reduced metabolic rate [4]
Abbreviations BMI, Body mass index
The cardioprotective effects of GLP-1 agonists could be a significant advantage for RA patients, who are at increased risk for heart disease. As that research continues, other questions that require interrogation involve the duration of therapy and whether GLP-1 receptor agonism will yield adverse events over the long term
But the sky-high demand for GLP-1 meds has created a booming market for compounded tirzepatide and semaglutide, especially since telehealth companies sell these meds for a fraction of the price of their name-brand counterparts
all administration guidance must come from the clinical trial protocol and IMP label