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MT-I vs MT-II: Melanotan I (afamelanotide) is more selective for MC1R, so it delivers the tanning effect with far less of the appetite-suppression and spontaneous-erection activity that MT-II produces at MC3/MC4 receptors but it is generally used more frequently to reach the same pigmentation [2]
doi:10.2337/db23-0377
Taking it on an empty stomach in the morning exploits the lower gastric pH present after overnight fasting
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
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