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2025 Aug;39(8):e70392
A proliferative probiotic Bifidobacterium strain in the gut ameliorates progression of metabolic disorders via microbiota modulation and acetate elevation
Perhaps most impressive, in the LEADER trial, the cardiovascular results of which were reported online in the New England Journal of Medicine in June 2016, approximately 9,300 patients with diabetes who were at high risk for cardiovascular disease were examined, and after five years, those who were taking Victoza had a lower rate of death due to cardiovascular disease, as well as lower rates of heart attack and stroke
Abstract The unprecedented clinical success of glucagon-like peptide-1 (GLP-1) receptor agonists has transformed the therapeutic landscape for obesity, diabetes, and cardiometabolic disease, while simultaneously reshaping long-standing perceptions of peptide-based therapeutics as biologically compelling but pharmacologically impractical
Semaglutide's main advantages are its proven cardiovascular benefit and lower injection site reaction rate
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