Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomised trial
Later on, dipeptidyl peptidase-4 (DPP-4) inhibition was identified as an effective way of raising endogenous GLP-1 levels [2]
From a medical and ethical perspective: Glutathione is not FDA-approved for skin whitening Any reported effect on skin tone is modest, dose-dependent, temporary, and reversible High doses may carry risks and require maintenance dosing, which is not aligned with ethical long-term dermatologic care At SkinDot Clinics, glutathione is discussed only as an antioxidant therapy, not as a cosmetic whitening, fairness, or brightening treatment
Anti-aging effects: DNA repair vs antioxidant protection NAD+ helps repair DNA damage as its main anti-aging mechanism
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