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PubMed laboratory research record [PMID: 21109554] PubMed record related to this compound for laboratory literature review
Unlike exogenous recombinant human growth hormone (rhGH), sermorelin stimulates physiologic GH production while preserving feedback regulation via somatostatin and IGF-1 pathways
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326 Within this context, activation of TLRs in macrophages deficient in mitogen-activated protein kinase kinase kinase 8 (MAP3K8, also known as COT or Tpl-2) leads to reduced phosphorylation of eukaryotic elongation factor 2 kinase (eEF2K), suggesting a pivotal role for MAP3K8 in regulating translation elongation
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