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5-Amino-1MQ targets the substrate binding site of NNMT the nicotinamide binding pocket competitively inhibiting nicotinamide methylation with an IC50 of 1.2 M under reference assay conditions

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Rinse-off products (shampoos, conditioners) don't provide enough contact time with the scalp to affect the follicles

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The two most relevant to hair are GHK-Cu and AHK-Cu