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Most published studies are small, involve patients affected by obesity and/or T2DM, and may therefore not be fully generalizable to the broader PsO/PsA population

Older adults (aged 65 years and above) are inherently more susceptible to postural hypotension due to age-related changes in baroreceptor sensitivity, reduced cardiovascular reserve, and higher prevalence of polypharmacy

OMIM 266130) is a rare autosomal-recessive metabolic disorder characterized by decreased glutathione (GSH) levels owing to defects in glutathione synthetase (GSS)

The ongoing SURPASS-CVOT trial will provide definitive evidence regarding cardiovascular safety and potential benefits

The concentration changed, not the compound stability