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There is no indication to date that the drug will be offered by the public health system or private plans in Brazil
As a result, the production of mature IL-1 was decreased following activation of NLRP3 by nigericin or ATP, with no effect on pyroptosis
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These therapies should never be positioned as replacements for established antihypertensive agents such as ACE inhibitors, ARBs, or calcium channel blockers
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