Using our single-cell mass cytometry approach, which allows us to detect CAR T cells in the context of the broader cellular BM background, we compared changes in metabolic protein expression over time between the pre-infusion products and the day 28 BM samples of the two cohorts
Previous work shows that DSIP can inhibit hypoxia-induced reduction of mitochondrial respiratory activity and suggests that DSIPs antioxidant mechanisms could contribute to its neuroprotective effects
PMID: 67 WangXHeQZhouCXuYLiuDFujiwaraNet al
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Most animal studies have focused on transplantation in sharp, unilateral, incomplete injury models (i.e., hemisection and hemicontusion) which present with limited neuron loss, immune response, and gliotic scarring of injury level (Wilcox et al., 2014)