Nevertheless, FSP1 has been less studied in the heart, where its relationship with ferroptosis and its precise function are poorly understood
Comparison of mechanism, pulsatility, and research applications
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This stability has made the peptide a useful research tool in experimental models investigating peptide signaling under physiologically relevant biochemical conditions
Mechanistically, necroptosis can be triggered by a variety of extracellular and intracellular danger signals, including tumor necrosis factor- (TNF-), Fas ligand, interferons, or Toll-like receptor (TLR) ligands (133)