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STEP 2 showed 1.0 mg kept about 73% of the 2.4 mg weight effect in type 2 diabetes with obesity. That is the clearest lower-dose weight evidence semaglutide has, though it is not the same as saying 1.0 mg equals 2.4 mg for everyone
The psychological stress of managing a dramatic body transformation, dealing with GI side effects, adapting to new eating patterns, and the anxiety about potential side effects like hair loss, can itself trigger or worsen telogen effluvium
Since the -2 subcluster is composed of cells exhibiting transcriptional signs of stress and the proportion of this subcluster was decreased upon liraglutide treatment, these data suggest that liraglutide-induced expression of XBP1 in the -1, -3, and -4 subclusters is a reflection of its protective action
But in 2025, it seems like thats not the case
Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance
