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The exact reason is unclear, but it may be related to Semaglutides effect on slowing gastric emptying or its interaction with the central nervous system, both of which could potentially trigger the hiccup reflex

Clinical effects of GLP 1 receptor agonists and dual incretin agonists

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18 By promoting the storage of fatty acids, such as triglycerides, PPAR acts as an insulin sensitizer and prevents ectopic fat accumulation

Reduced testosterone levels : Lower insulin means less stimulation of testosterone production