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Tirzepatide appears to have a peculiar impact on atherogenic dyslipidemia compared to GLP-1R monoagonists, with a preferential benefit on triglyceride levels [78, 79]
In the semaglutide group, lower baseline body weight and waist circumference were each associated with a 4% lower MACE risk per 5 kg or 5 cm decrement, respectively
This stepwise approach is intentional
Tong J, DAlessio D
Loss of lean mass presents two challenges
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