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J Physiol 587(1):4960 Nectow AR et al (2017) Identification of a brainstem circuit controlling feeding

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Clinical trials demonstrate these medications decrease triglycerides by 15-25%, lower LDL cholesterol by 3-7%, and modestly increase HDL cholesterol

For example, a 10-unit error at 5 mg/mL concentration represents 0.5 mg of semaglutide, while the same 10-unit error at 1 mg/mL represents only 0.1 mg