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The problem centers around compounded semaglutide, a generic version of Wegovy or Ozempic sometimes given to patients when the brand names are not available due to shortage
In one case, we were recommended GLP-1s even though the user was underweight (57 and 110 pounds)
However, the drug-specific mechanism of action and the precise dose-response relationship still need to be further clarified [60]
While GLP-1RAs may be promising as an adjunct therapy for these HS patients, further investigation is needed to elucidate the degree to which weight reduction and metabolic/inflammatory modulation contribute to their therapeutic potential before their routine use can be recommended
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