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Blue Cross Blue Shield and other major insurers frequently require prior authorization before covering tirzepatide, a GLP-1 receptor agonist shown in clinical trials to reduce body weight by 20% or more

For example, CordenPharma announced a collaboration with PeptiSystems in 2022 that involved a continuous manufacturing synthesis approach for GLP-1RAs that reduces solvent consumption and corresponding waste production by 40%

A combination approach may be worth considering

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A 12-week supply can run you about $1,190, while a ten-week schedule for semaglutide with added B vitamins is closer to $1,895