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It is an imbalanced agonist with GIPR potency close to native GIP but weaker GLP-1R affinity, and shows biased GLP-1R signaling, favoring cAMP over -arrestin recruitment
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doi: 10.7150/THNO.71360 13
GLP-1 drugs work by mimicking a natural hormone in the body that helps to regulate blood sugar levels and appetite
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