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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies

If you are going to self-administer at home, your healthcare provider or nurse will teach you proper technique

Dror and Allen, 2008 Effect of vitamin B12 deficiency on neurodevelopment in infants

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